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Aspartic acid

Posted on 09. Jan, 2011 by .

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Aspartic acid,also called asparaginic acid, also known as L-aspartate, is thought to help promote a robust metabolism, and is sometimes used to treat fatigue and depression. Aspartic acid plays an important role in the citric acid cycle, or Krebs cycle, during which other amino acids and biochemicals, such as asparagine, arginine, lysine, methionine, threonine, and isoleucine, are synthesized.

Aspartic acid gets its reputation as a treatment for chronic fatigue from the crucial role it plays in generating cellular energy. Aspartic acid moves the coenzyme nicotinamide adenine dinucleotide (NADH) molecules from the main body of the cell to its mitochondria, where it is used to generate adenosine triphosphate (ATP), the fuel that powers all cellular activity.

In short, the more NADH a cell has, the more chemical fuel it produces, and the more energy you have to get through your day. (Some studies have shown that aspartic acid actually increases both stamina and endurance levels in athletes.) In addition, this amino acid helps transport minerals needed to form healthy RNA and DNA to the cells, and strengthens the immune system by promoting increased production of immunoglobulins and antibodies (immune system proteins).

Aspartic acid keeps your mind sharp by increasing concentrations of NADH in the brain, which is thought to boost the production of neurotransmitters and chemicals needed for normal mental functioning. It also removes excess toxins from the cells, particularly ammonia, which is very damaging to the brain and nervous system as well as the liver.

A non-essential amino acid in protein. The body produces aspartic acid to form part of a liver enzyme that builds and breaks down proteins and amino acids, and detoxifies nitrogen in urea. Aspartic acid is a neurotransmitter.Aspartic acid is a non-essential amino acid, which means that the body is able to manufacture its own supply. It is also found in dairy, beef, poultry, sugar cane and molasses (the artificial sweetener aspartame is made from aspartic acid and phenylalaline, another amino acid). People with diets low in protein or with eating disorders or malnutrition may develop a deficiency, not only in aspartic acid, but in other amino acids as well, and experience extreme fatigue or depression.

Serious athletes may need to take an amino acid supplement as well—aspartic acid can be found in protein supplements such as amino acid tablets and whey protein powder drinks/bars, and are often marketed as energy boosters. They are generally available at most drugstores and health food stores, or at your local gym or health club.

Aspartic acid and health

* Liver health – aspartic acid benefits the liver by removing excess ammonia from the liver. Aspartic acid combines with other amino acids to form molecules that absorb toxins and remove them from the bloodstream
* Chronic fatigue syndrome – since aspartic acid increases stamina, it is good for fatigue (chronic fatigue syndrome may result from low levels of aspartic acid, because this can lead to lowered cellular energy)

Aspartic acid works best with

* Vitamin B6 (Pyridoxine)
* Magnesium
* Potassium
* Arginine
* Glutamic Acid

Aspartic acid is considered generally safe, however, a small number of people may experience an allergic reaction to supplementation with aspartic acid. Women who are pregnant or breast-feeding should not use aspartic acid supplements. Always avoid taking individual amino acids in high dosage for prolonged periods.

Aspartic Acid is widely used in food and pharmaceutical industry as an important amino acid. It is used as dietetic supplement, additive for kinds of soft drink. In medicine, it is used as ammoniac detoxicating agent. hepar function accelerator and fatigue refresher

Description: White crystals or crystalline powder having a slightly acid taste. It is slightly soluble in water. It is soluble in acid, alkali and salt water,but dissoluble in alcohol and in ethyl ether.

Side Effects, Toxicity and Interactions:

The use of a single amino acid supplement may lead to negative nitrogen balance, decreasing the metabolic efficiency and increasing the workload of the kidneys. In children, taking single amino acid supplements may also harmfully affect growth parameters.

Always avoid taking individual amino acids in high dosage for prolonged periods.

Women who are pregnant or breast-feeding should not use aspartic acid supplements.


thank you and references

http://www.nlm.nih.gov/medlineplus/ency/article/002234.htm
http://www.vitaminstuff.com/amino-acid-aspartic-acid.html
http://www.healthvitaminsguide.com/aminoacids/aspartic-acid.htm
http://www.greenfacts.org/glossary/abc/aspartic-acid.htm
http://www.vitamins-supplements.org/amino-acids/aspartic-acid.php
http://www.stjohnprovidence.org/HealthInfoLib/swArticle.aspx?19,AsparticAcid
http://www.greatvistachemicals.com/amino_acids/L-aspartic_acid.html

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